Sunday, March 14, 2010

Rabbit Monoclonal Antibodies Developed for Immunohistochemistry Applications


A new range of rabbit monoclonal and polyclonal antibodies has been developed for immunohistochemistry (IHC) applications. A rabbit custom antibody service is also available.

Antibodies produced by rabbits are reported often to provide superior antigen recognition, greater specificity, and better consistency than those offered by mice. Rabbit antibodies can recognize specific antigens and epitopes that are not immunogenic in mice or rats. These antibodies can sometimes also offer higher working titers and may therefore help to lower laboratory costs. By using rabbit monoclonal antibodies (RMAbs), researchers can benefit from these unique qualities especially in the area of immunohistochemistry. Use of RMAbs technology provides critical information to researchers regarding the distribution and localization of biomarkers, and differentially expressed proteins in different parts of a biologic tissue.

AMSBIO (Abingdon, UK) offers a range of over 3,500 antibodies for immunohistochemistry including rabbit monoclonal, polyclonal, and mouse monoclonal antibodies (MAbs). Included in this range are antibodies that have been characterized to work on FFPE sections, renowned for their robust, highly sensitive, and specific characteristics. Many of these antibodies have been CE marked. The AMSBIO SP1 Estrogen Receptor antibody is now recommended as the gold standard by leading breast cancer experts and distributed worldwide.

AMS Biotechnology (AMSBIO) is a leading international provider of products and custom services for life sciences research. The AMSBIO range includes over 23,000 polyclonal and monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, tissue DNA, RNA, protein, and microarray products. Key research areas include apoptosis, cell invasion and migration, cell signaling, DNA damage, electrophoresis, glycobiology, posttranslational modification, and stem cell biology.

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